Objectives: To compare the effect of myofascial trigger point release and ultrasonic therapy in trigger points of upper trapezitis. Design: Experimental design with randomized control trial type Setting: The study was conducted at SRM Medical Hospital & Research Center, Kattankulathur. Procedure: 30 subjects diagnosed with upper trapezitis, were divided into two groups, each group is given with different treatment method, one with myofascial trigger release where as other with ultrasonic therapy. Results: The results shows that there was significant difference between two groups of pre and post-test and value of P<0.001. Conclusion: After intervention of both the groups pain was reduced ,range of motion and muscle length increased.