The diversity of pathologic processes that may reside in a small anatomic compartment like mediastinum is impressive. The lesions may be neoplastic and non-neoplastic; and may include proliferation of somatic epithelial, lymphoid, mesenchymal and germ cell types. Anterior mediastinum is the preferred site for mediastinal masses, of which 40% or more are of thymic origin. Again approx. 90% of all thymic masses are in the anterior mediastinum. About 40-50% of patients having anterior mediastinal mass are asymptomatic and when symptoms appear, those are mostly due to structural compression and displacement. These neoplasias are most common in the fifth and sixth decades of life and distributed evenly between men and women. In the present case study autopsy was performed in a case of sudden death, which had history of respiratory distress for some time and was being treated elsewhere by quacks. A huge anterior mediastinal growth was found on autopsy and diagnosis was confirmed by histopathology and immunohistochemistry.
