Dietary composition is one of the major experimental factors that affects many aspects of animal physiology including life span, general health, reproductive fitness and progeny sex ratio hence the present study has been undertaken in Drosophila melanogaster to investigate the effect of creatine monohydrate supplemented media on sex ratio. In the present study, the results showed that flies fed creatine monohydrate treated media produce greater number of female offspring than male offspring while control media produced almost equivalent number of female and male progenies. It was observed that the progenies of flies maintained on 2.5% creatine monohydrate supplemented media had a sex ratio similar to that of control. Thus this study suggests that the increased diet supplementation with creatine monohydrate increases the number of female offspring in Drosophila melanogaster.
