Oligodontia designates the congenital absence of six or more permanent teeth, excluding the third molars. The etiology behind this may be environmental and genetics factors. Genes responsible for non syndromicoligodontia are found to be MSX1 and PAX9 genes.The present case report describes a case of multiple agenesis of permanent teeth in a 14 year old female, with a positive family history. On examination, there was no abnormality in either hairs or nails, perspiration was normal and no congenital clefts of lip or palate was seen. Hence in this case it is not associated with any syndrome and was familial in nature.
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