Objectives: To determine the effect of herbal medicine therapy on decreasing of IgG anti-TORCH and comparison of the effectiveness of herbal therapy based on IgG titer group. Design: Experimental Study with Pre-Post Study Design Setting: The study was conducted at the Clinic of Aquatreat Therapy Indonesia Yogyakarta. Procedure: 255 subjects diagnosed with TORCH infection, were divided into three groups, each group was given with same treatment method using herbal medicine which Curcuma mango (White Turmeric), Catharanthus roseus (Rose Periwinkle), Phaleria macrocopra (Gods Crown), Curcuma longa (Turmeric), and Morinda sp. (Noni). Result: The result showed that there was significant in Cytomegalovirus (CMV) groups of pre and post test to decreases of IgG titers in patients with CMV with the value of asymp. Sig (2-tailed) <0.00. Conclusion: Herbal medicine therapy at Klinik Aquatreat Therapy Indonesia was effective to reduce the titer of IgG of TORCH patients within 3 months. The results of this research show the best effectiveness are CMV and Toxoplasmosis groups.
