Dissemination of new delhi metallo-β-lactamase (blandm) gene in pseudomonas aeruginosa isolates from burn center in najaf, Iraq

Carbapenems are the most potent β-lactams and widely used as the mainstay and empirical for treatment of MDR P. aeruginosa. Carbapenems resistant P. aeruginosa has now emerged and is disseminating worldwide.Identified blaNDMin the isolates of P. aeruginosa, that are recovered from Burn Center in Najaf.Cross- sectional study involved 123samples were collected from Burn Center in Najaf. All samples culture on blood and MacConkey agar, and then isolation and identification by conventional methods and confirmed by VITEK-2 compact to diagnosis P. aeruginosa. The antimicrobial susceptibility test for 13 antibiotics were tested by using MIC method.35P. aeruginosaisolates from 123 samples taken from Burn Center (28.5%), 22/35 (63%) isolates carbapenem resistant P. aeruginosa (CRPA), there were 8/22 (36.4%) of samples positive for blaNDM gene. The findings of this study underscore the high prevalence of NDM-type MBL among carbapenemase producing isolates.