Bone scan is the accepted initial imaging modality for skeletal metastases. Some patients use chemotherapy in the initial stages before and after surgery for breast cancer patients according to the international protocol, this study aimed to evaluate the time elapsed between bone scan and chemotherapy dose. It is a retrospective study designed and conducted in the Nuclear Medicine Department, Radiation and Isotopes Center of Khartoum. (RICK) which included 50male and female cancer patients with age ranged between 25-90 years, weighing 40-90kg were used in the study. All patients were diagnosed as breast cancer according to the histopathology report and were received all chemotherapy treatment. The results of this study revealed that the most common drugs used for adjuvant and nanadjuvant chemotherapy and there are a direct linear relationship between the acquired counts and the elapse time after chemotherapy , the coefficient of this relationship indicates that the count will be increased by 0.018 mega counts per day starting from 0.81 mega counts.ther is a direct positive relationship between the patient weight (kg) and the administered dose (mci) ,when the weight of the patient increase must be increasing the doses. This study concluded thatthe suitable time of bone scan post chemotherapy is one month and chemotherapy would lead to more influence on the bone scan.
