Background: The village midwife is a midwife profession that is placed in all villages in Indonesia as government health workers. The aim is to help reduce maternal and infant mortality. But in reality, infant and maternal mortality rates are still high. Infant deaths in 2010 were mostly due to asphyxia neonatorum 27%. Thus, the role of village midwives is very important in managing neonatal asphyxia and reducing infant mortality. This study aims to analyze the performance factors of village midwives, in the management of neonatal asphyxia. The research design is quantitative research, analytic observational research with cross sectional approach. Data collection was carried out using a structured questionnaire. The questionnaire was tested for validity and reliability. Population: village midwife in a Regency, totaling 65 respondents. Samples were selected by purposive random sampling. The analysis used was the Chi Square test and multiple logistic regression. Results: The average age of respondents was 35 years old, Diploma 3 education: 96.9%; Less knowledge: 72.3%; less attitude: 55.4%; have less motivation: 50.8%. Support of resources (funds, facilities, infrastructure) 80% good. Multivariate analysis showed a joint relationship between knowledge (Exp. (B) 7,723) and motivation (Exp. (B) 8,324) with the performance of village midwives in the management of neonatal asphyxia. Conclusion: Need continuous technical guidance, in the management of neonatal asphyxia. It is necessary to provide and increase the motivation of village midwives through rewards, especially for those who work well in handling neonatal asphyxia.
