Objectives: The objectives of the article is to emphasis on the need of adult immunization which is felt need due to present era of resistance stain to majority of antibiotics, increase risk of communicable diseases because of mutation, new stains, globalization and migration thereby, difficult to manage infectious diseases. Introduction: Since the start of the January this year, a new outbreak of SARS-CoV-2 disease has been reported worldwide with no specific medication, vaccination being only hope is an eye opener about adult vaccination as a paradigm shift to well being. Methods: It is predicted that if nearly 20% of the population were to get infected, the direct medical expense, considering expense only during the course of the infection, it could be as high as $163.4 billion which can be prevented by effective vaccination. Results: Adapting a standard adult immunization regime along with emphases on life course immunization as a integral component in nation programs for the better well being of present as well as future generation along with proper education of health care workers about the various adult vaccination and their important which will help in resolving the gap by able to proceed with vaccination without difficulty, thereby enhancing adult population confidence, removing the unawareness , and being mindful about cultural acceptance. Conclusion: Over all, improving adult vaccination coverage in India, it could help us to reduce the overall burden of disease among the adult population by reducing hospital admissions, health costs, and mortality rates, and improving quality of life.
