Background: Cardiovascular diseases are the first leading cause of death for adult men and women in developed countries. Surprisingly in developing countries CVD also become the first leading causes responsible for one third of all deaths. Aims and Objectives: To evaluate the level of Seum GGT, S.uric acid and S. electrolyte in myocardial infarction patients. Material and Methodology:100 patients of MI and 50 age matched healthy controls are involved in this study. Estimation of GGT, Uric acid, S. electrolyte was done from all participant. Results obtained are analysed statatically by calculating p-value using online student t-test calculator. P-value less than 0.01 was consider as a significant. Result:S.GGT(IU/L),S.uricacid(mg/dl),S.sodium(mmol/l),S.pottasium(mmol/l),S.sodium(mmol/l),S.pottasium(mmol/l),S.chloride(mmol/l) in case group is 28.12±14.72, 7.11±1.08, 135.45±2.16, 3.43±0.35, 105.97±3.6 respectively and in control group is 11.09±3.8, 4.2±0.79, 142±2.76, 4.5±0.37, 103.62±2.01 respectively Conclusion: In conclusion our study indicated a direct association between serum GGT and uric acid in MI .Although GGT is often measured as a marker of liver health, this study provides evidence that it may also be useful in the identification of patients at elevated risk of MI.