Diseases affect people physically, emotionally, socially and also economically. As contracting and living, a disease can alter one's perspective on life, and one's personality. Societies with a heavy burden of disease tend to experience a multiplicity of severe impediments to economic progress. Ill health in a family member can create situational crises that can lead to emotional distress throughout the family and also the effect of disease will have serious consequences on the ability of the family to support itself at some socially acceptable level. So, the present study was planned with an objective to investigate the psychological and social consequences caused by lifestyle diseases. Exploratory research design was followed in the present study. The twin cities of Hyderabad and Secunderabad were purposively selected identifying the sample (100) based on Lifestyle diseases experienced by the family members. Survey research method was adopted by using questionnaire and also personal interview technique to elicit the information. Statistical procedures like frequencies, percentage and chi-square tests, were employed to analyze and interpret the data. The results of the study observed that out of 100, nearly 85% of the respondents’ psychological and 35% of social well being was affected due to their ill health conditions.