Statement of problem: Delayed loading is one of the concerns of implanted patients. Immediate loading can solve the problem and make patients more satisfied. Objective: The present study aimed to compare the removal torque of maxi implants under different loading (immediate and delayed) patterns. Materials and methods: This split mouth experimental study included 2 dogs. Impressions were made and then all premolars were extracted under general anesthesia. After a three months healing period, 3 implants were inserted in each quadrant (12 implants). Anterior and posterior implants (case group) were splinted by an acrylic temporary bridge, in order to make middle implants (control group) off the occlusion. Dogs were sacrificed after 6 weeks and bone blocks were submitted for removal torque test. Data were analyzed using ANOVA test (P<0.05). Results: Mean torque values for the cases and the control groups were respectively 46.82±25.58 and 59.88±15.19 (p value=0.582; not significant). Conclusion: It may be concluded that immediate loading does not effect on reducing the reverse torque values of the Maxi implants. This supports the advantages of immediate loading for Maxi implants.