Bacterial contamination does not necessarily mean infection", was presented at the 17th World Meeting of the International Union of Phlebology American College of Phlebology, in 2013, Boston (USA). A common mistake made by physicians, when there is an unfavourable clinical course of the wound, is to confuse contamination with wound infection, then, they ask for a bacteriological swab and there are three possibilities: A/ Prescribe antibiotics before knowing the test result. B/ Prescribe antibiotics after knowing the test result, C/ Prescribe no antibiotics and healing the ulcer. This is a clinical experience in more of 150 patients with vascular leg ulcers, which were healed by means of using a compression technique, called “Double focal compression bandaging”, without using any kind of antimicrobial agent, This technique is based on physiological concepts such as arteriogenesis and angiogenesis.