An electrochemical characteristics of promethazie hcl using ion Selective electrodes

The highly selective and sensitive PVC based membrane sensor was fabricated by using 1,3,5-tris [(2,3-dihydroxybenzylamino) amino methyl]cyclohexane (L) as a neutral membrane carrier for the potentiometric determination of Promethazine HCl. The membrane with the composition of33% PVC, 64% Plasticizer, 3% PM-PMD (Ionophore) and 1% NaTPB was found to be best in terms of response characteristics of sensor assembly. The proposed membrane sensor has very low detection limit of 2.0 x 10-8 M, within the concentration range of 5.0 x 10-8 – 1.0 x 10-2 M, and has fast response time of about 10s. The proposed sensor was used for the selective determination of Promethazine HCl. in different synthetic as well as real sample.

Sharma, B.D. and Seema Rani
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Int J Inf Res Rev
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