The purpose of the study was to find out the effect of allium sativum (garlic) consumption on total cholesterol. To achieve this purpose of the study, thirty subjects were selected from department of Physical Education and Sports Sciences, Annamalai University, Annamalainagar, India. The selected subjects were the age between18 to 25 and they were examined by a qualified physician and certified that they were medically and physically fit to participate above programme. The selected subjects were randomly divided into three groups of 10 subjects each group. Group one acted as control group, experimental group I (placebo) and experimental group II (garlic consumed group). The experimental group subjects were underwent regular practice for five weeks. The subjects were tested on selected criterion variable such as total cholesterol prior to and immediately after the training period. The analysis of covariance (ANCOVA) was used to find out the significant differences if any, between the experimental group and control group on selected criterion variable. The result of the present study has revealed that there was garlic has the effect to decrease the level of cholesterol among college men.